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Related
issue: Cannabis and mental illness - here
On
March 18th the Independent on Sunday changed its mind about supporting
legalisation of cannabis with what must have been one of the worst
examples of factless reporting ever carried by a supposedly "quality"
newspaper.
The
stated reason for the change of mind concerns the nature of cannabis
now available in the UK. Cannabis, they claimed is now 25 (or 30
depending which item you read) times stronger than it was during
the 60's. This "new" type of cannabis has apparently resulted
in thousands of "cannabis addicts" and a surge in mental
illness.
So
what is the truth about cannabis strength, how has it changed over
the years? To answer that question, we need to understand a little
about what cannabis is and how the authorities have treated it over
the years.
How
is cannabis strength measured?
Definition:
Strength is the amount of drug per volume or weight of a sample.
By way of illustration alcohol strength is measured in "ABV"
- the percent of alcohol per volume, so a 5% beer will contain 5%
alcohol, easy.
As
the drug the government associates with cannabis intoxication is
THC and we're dealing with a solid substance, the strength of cannabis
would be expected to be measured in Mg THC per gram of sample, that's
where we hit a problem.
Now
it's worth mentioning that cannabis is not simply THC, it's a blend
of various active substances, the different ratios of which produce
a very different effect on the user. However, only THC is usually
measured, which produces the first problem when we want to examine
changes in the nature of cannabis over time. No measurements of
the amounts of the other active chemicals have ever been made by
the authorities on anything like a regular basis. This is at least
in part explained by the fact that cannabis is illegal and what
measurements there have been made have been first and foremost for
enforcement, not quality control reasons.
However,
at least the strength of cannabis has been measured in terms of
THC per gram of sample? Sadly, no it hasn't.
In
2005, UKCIA asked the government's anti drug advertising agency
"Talk to Frank" how cannabis strength is measured, we
were asked to write to the Home Office:
| UKCIA
question:
Further to a phone chat today (Thursday 19th May) to
one of your people
I've been hearing a lot about the strength of cannabis
of late. This strength has been quoted as "percent
THC", can you explain what this means?
With alcohol, strength is measured in percent alcohol
by volume (%ABV), but clearly the THC in cannabis doesn't
amount to 10% of the volume nor of the weight, so what
is it a percentage of?
As a follow-up question, cannabis isn't simply THC,
the other main component is CBD which is known to modify
the effects of THC. I have also
seen this ratio reported as a percentage, so how is
the ratio of THC to CBD measured?
Many thanks
-----------------------------
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Home
Office reply:
Thank you for your email of 19 May which has been passed
to me for reply.
The percent THC is the weight for weight of THC in the
dry cannabis sample selected for analysis. A fresh cannabis
plant contains a lower proportion
of THC as fresh plant material contains a lot of water.
THC is the main active constituent of cannabis. The.proportion
of other constituents of cannabis is therefore not of
interest in terms of potency.
The THC acid (delta-9-tetrahydrocannabinolic acid) is
converted to THC when cannabis is heated (e.g. in a
cigarette) so some scientists use gas chromatography
(GC) analysis to measure THC. This method. effectively
measures the total available THC, as the sample is heated
in the injection port of the GC.
Ratios of cannabinoids are sometimes measured when comparing
cannabis samples. The ratios are relative responses.obtained
by the particular method of analysis and so do not directly
relate to actual ratios of the percentage compositions.
Absolute proportions of CBD would not normally be measured.
Richard Mullins
Drug Legislation and Enforcement Unit
Home Office
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So
what does the above tell us?
"The
percent THC is the weight for weight of THC in the dry cannabis
sample selected for analysis. A fresh cannabis plant contains a
lower proportion of THC as fresh plant material contains a lot of
water."
It's
unclear what they mean by "dry". Plant material, of the
sort you might buy from your dealer - even if dry in the normal
sense - is still composed largely of water, so what do they mean
by "dry"? It would seem that what they're talking about
is a desiccated sample, that is a sample in which all the water
has been removed, in effect destroying the biomass material, leaving
the oils produced by the plant. We did ask for confirmation on this
point, but received no answer.
It's
also worth pointing out here that the measurement is actually referred
to as "potency", not strength. This careful use of words
is typical of the Home Office when it's being economical with the
truth. The reason this is important is because the amount of oils
the plant produces is not a constant fraction of the overall weight.
It will depend on which part of the plant is sampled and how it's
grown.
So
the measurement they make is a percentage by weight of the oils
in the sample, not of the overall weight of the sample.
Is
potency directly comparable to strength? It's not clear that it
is. In which case, the strength of cannabis over the years has never
really been measured. It's also apparent from the reply that no
standard system for making the measurement has been employed ("some
scientists use gas chromatography")
Based
on this type of measuring regime, it's clear that making meaningful
conclusions about changes in strength is going to be difficult.
How
are samples selected for measurement?
Here
we hit perhaps the biggest problem as no statistically valid monitoring
of the cannabis on sale has ever happened. What measurements have
been taken have been made on samples seized by the police in raids.
How representative these samples are of the general situation is
unknown, but as a sampling method it wouldn't be considered reliable
enough for serious scientific analysis.
So:
to recap:
The
property measured - "potency" - bears an uncertain relation
to "strength"
There has been no standard methodology for making the measurements
over the years.
The samples measured are unlikely to be a statistically valid sample.
So
what conclusions can be drawn from all this?
The
most authoritative study in recent times was conducted by the European
Monitoring Centre for Drugs and Drug Addiction in 2004 - read it
here.
The
report makes it clear that the data is somewhat unreliable and it's
therefore difficult to draw firm conclusions, but it accepts there
has always been strong cannabis which can compare to today's offerings.
It makes the point that home grown is going to be fresher and thus
stronger (cannabis "goes off" with time as the THC breaks
down).
There
is undoubtedly some strong cannabis available these days, but there
always has been. It's reasonable to suppose that, because it's fresher
there will be a higher proportion of stronger samples (= better
quality), but overall there is no evidence to support the claims
of a massive increase in strength.
It
should also be mentioned that commercial supplies of cannabis -
herbal and hash - are often highly contaminated these days, a direct
result of police action aimed at disrupting the supply. It's therefore
obvious that most consumers aren't getting the higher value strong
product.
Has
there been any other change in Cannabis over the years?
The
most obvious change in recent times in the UK has been the move
from imported hash to "home grown" herbal. Originally
of course, cannabis was grown outside in fields by people who had
a long social history of using it, they knew what they were growing.
These days most of the cannabis supplied commercially is grown intensively
under lights, perhaps with the use of chemicals such as pesticides.
The motivation for large scale grow ops of course is turnover and
profit. How these plants compare with the original truly organic
product is unknown. As we've never monitored the total composition
of the product, we have no way of knowing if there is a difference.
It
should be pointed out however that the cannabis grown under lights
is still cannabis. Despite some claims in the press, it isn't "genetically
engineered" or otherwise mutated. However, it's also fair to
point out that the strains have been selected to grow well under
these conditions.
Conclusion
No-one
has a
clue what's going on to be blunt. Prohibition has prevented any
proper monitoring of the commercial supply and it's produced a potentially
significant change in the way the cannabis is grown.
The original supply of naturally grown cannabis has been all but
eradicated because of prohibition and prohibition has created the
market for the new versions of so-called "skunk".
Given
that the present regime is the root of so many uncertainties and
the cause of so much ignorance, the Independent on Sunday's new
found support for prohibition makes little sense.
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