Research Index | Medline Index
Cannabis Research - psychosis & schizophrenia
- Authors
- Taschner KL
- Title
- [Psychopathology and differential diagnosis of so-called Cannabis
psychoses].
- Language
- German
- Source
- Fortschritte der Neurologie-Psychiatrie
- Date
- 1983 Jul
- Issue
- 51(7)
- Pages
- 235-48
- Abstract
- From 237 patients examined for drug-induced psychoses, 50 cannabis
psychoses were examined according to the criterion "main cause of
addiction" and 107 were examined according to the criterion
"consumption during the last three months before hospitalization".
The cannabis psychoses were compared to the other drug-induced
psychoses as well as to a control group consisting of 219
schizophrenic patients. General agreement was found with the other
drug-induced psychoses as well as with the group of schizophrenic
patients. The variation from the symptomatology of the
schizophrenics is generally common to both the cannabis psychoses
and the other drug-induced psychoses. Judging by the results of our
investigations, it must be concluded that there is no disease
"cannabis psychosis" in its own right, just as the disease
"drug-induced psychosis" also does not exist in its own right. While
there is a certain slight drug-specific psychopathological
undertone, it does not entitle us to speak of a syndromatic or
indeed a nosological entity. The psychopathological cross section
does not permit a differentiation in the individual psychoses groups
mentioned, although this has often been attempted in the literature.
That there are no relevant psychopathological differences between
cannabis psychoses and endogenous schizophrenia could, for one, be
based on the fact that we are observing the final stage of one and
the same underlying pathological process. In this case both
syndromes would in practice be endogenous psychoses, with the cause
not being known in one case. The psychopathologic similarity of
these two psychoses forms could, however, also be based on the
assumption that cannabis psychoses are triggered schizophrenias, so
that we could in both cases be dealing with one and the same
disease. We see the solution to the problem of diagnosing
symptomatic psychoses, and in particular cannabis psychoses, in
making a diagnosis that takes the etiology into consideration in
addition to the syndrome diagnosis.
- Authors
- Mathers DC, Ghodse AH, Caan AW, Scott SA
- Title
- Cannabis use in a large sample of acute psychiatric admissions.
- Source
- British Journal of Addiction
- Date
- 1991 Jun
- Issue
- 86(6)
- Pages
- 779-84
- Abstract
- A sample of 908 patients drawn from two London Psychiatric Hospitals
is described in terms of age, sex, self-reported drug and alcohol
history, drug urinalysis results and initial psychiatric diagnosis.
Some (34.5%) of respondents admitted to using cannabis at least once
in their lifetime and 13% of those tested had urines positive for
cannabis on admission. Cannabis use is commoner in young males.
These is a higher likelihood that an initial diagnosis of
'psychosis' will be made at admission if patients either report use
of cannabis or present a urine sample positive for cannabis.
- Id Code
- 91059143
- Authors
- Lewis G, Croft-Jeffreys C, David A
- Title
- Are British psychiatrists racist? [see comments].
CM - Comment in: Br J Psychiatry 1990 Dec;157:936-7, Comment in: Br J
Psychiatry 1991 Jan;158:135, Comment in: Br J Psychiatry 1991
Feb;158:289-90
- Source
- British Journal of Psychiatry
- Date
- 1990 Sep
- Issue
- 157
- Pages
- 410-5
- Abstract
- Out of a sample of 220 British psychiatrists, 139 completed a
questionnaire regarding a case vignette of psychotic illness. The
sex and 'race' of the vignette were varied and the responses
compared. The Afro-Caribbean case was regarded as that of an illness
of shorter duration, and requiring less neuroleptics than the white
case. Respondents judged the Afro-Caribbean case as potentially more
violent and thought criminal proceedings were more appropriate. The
female vignette was perceived as less violent, less criminal, and
less likely to need neuroleptics. Cannabis psychosis and acute
reactive psychosis tended to be diagnosed more often and
schizophrenia less often in Afro-Caribbean cases, refuting the claim
that psychiatrists tend to overdiagnose schizophrenia in this group.
Such 'race thinking' (a form of stereotyping which is distinct from
ideological racism) could lead to inappropriate management.
- Id Code
- 94356351
- Authors
- Thomas H
- Title
- Psychiatric symptoms in cannabis users [see comments]. [Review]
CM - Comment in: Br J Psychiatry 1993 Nov;163:698
- Source
- British Journal of Psychiatry
- Date
- 1993 Aug
- Issue
- 163
- Pages
- 141-9
- Abstract
- The usual phenomena of cannabis intoxication include experiences
which in a non-intoxicated state would be considered as psychiatric
symptoms. These can be distinguished from adverse reactions to
cannabis, the commonest of which is an acute anxiety state. Acute
psychotic episodes can also follow ingestion of the drug but are
infrequent. These can be classified as acute confusional states and
episodes occurring in clear consciousness. Neither presentation
consistently shows enough specific features to warrant the diagnosis
of 'cannabis psychosis' as a distinct clinical entity. The evidence
that cannabis has a causative role in chronic psychotic or affective
disorders is not convincing, although the drug may modify the course
of an already established illness. Further controlled studies would
be required to clarify the aetiological significance of the drug in
these conditions.
- References
- 90
- Id Code
- 88061263
- Authors
- Schneier FR, Siris SG
- Title
- A review of psychoactive substance use and abuse in schizophrenia.
Patterns of drug choice. [Review]
- Source
- Journal of Nervous & Mental Disease
- Date
- 1987 Nov
- Issue
- 175(11)
- Pages
- 641-52
- Abstract
- We reviewed studies measuring unsupervised use of psychoactive
substances in schizophrenic and control populations and organized
the results by substance class. Despite much variation in their
methodologies, these studies broadly agreed that schizophrenic
groups' use of amphetamines and cocaine, cannabis, hallucinogens,
inhalants, caffeine, and tobacco was significantly greater than or
equal to use by control groups consisting of other psychiatric
patients or normal subjects. Schizophrenic groups' use of alcohol,
opiates, and sedative-hypnotics was significantly less than or equal
to use by control groups. We discuss the implications of this
nonrandom pattern of drug choice for the hypothesis of substance
abuse as a form of self-medication in schizophrenia. [References:
93]
- Id Code
- 95078211
- Authors
- McGuire PK, Jones P, Harvey I, Bebbington P, Toone B, Lewis S, Murray RM
- Title
- Cannabis and acute psychosis.
- Source
- Schizophrenia Research
- Date
- 1994 Sep
- Issue
- 13(2)
- Pages
- 161-7
- Abstract
- The Present State Examination was used to assess the psychopathology
of 23 psychotic patients who were cannabis positive on urinary
screening, and 46 matched drug-free controls. Cases and controls
were indistinguishable in terms of psychopathology, DSMIII
diagnoses, onset of recent illness, the proportion of first
admissions, ethnicity, and socio-economic class, differing only in
their histories of substance use. These data suggest that psychosis
which develops or recurs in the context of cannabis use does not
have a characteristic psychopathology or mode of onset, and is not
restricted to a particular ethnic or socio-demographic group. There
is thus little evidence to support the validity of 'cannabis
psychosis' as a diagnostic entity.
- Id Code
- 92180676
- Authors
- Peralta V, Cuesta MJ
- Title
- Influence of cannabis abuse on schizophrenic psychopathology.
- Source
- Acta Psychiatrica Scandinavica
- Date
- 1992 Feb
- Issue
- 85(2)
- Pages
- 127-30
- Abstract
- A study was carried out on a group of 95 schizophrenic patients
(DSM-III-R criteria) under the age of 35, 23 of whom were cannabis
abusers in the past year. The objective of the study was to evaluate
the effect of cannabis on positive and negative schizophrenic
symptoms, evaluated using Andreasen's Scales for the Assessment of
Positive and Negative Symptoms (SAPS and SANS). There were no
statistically significant differences between the groups on the
SAPS; the group of cannabis abusers had higher scores except for the
delusions subscale. On the SANS nonabusers scored higher, with a
significant difference on the alogia subscale. The results suggest
that the consumption of cannabis by schizophrenic patients could
attenuate negative symptoms, which would support the self-medication
hypothesis of cannabis abuse.
- Authors
- - Gruber AJ, Pope HG Jr, Brown ME
- Title
- - Do patients use marijuana as an antidepressant?
- Language
- - Eng
- Date
- - 1996
- Issue
- - 1062-6417
- Source
- - Depression
- Pages
- - 77-80
- Country
- - UNITED STATES
- Abstract
- - Several lines of evidence suggest that cannabis may have antidepressant
effects. However, methodologic limitations in available studies make
the results difficult to interpret. We review this literature and
present five cases in which the evidence seems particularly clear that
marijuana produced a direct antidepressant effect. If true, these
observations argue that many patients may use marijuana to "self-treat"
depressive symptoms.
- Research Institute
- - Biological Psychiatry Laboratory, McLean Hospital, Belmont,
Massachusetts 02178, USA.
- References
- - 34
- Source
- - Depression 1996;4(2):77-80